Mission
The Genomic Technology Core develops novel single-cell genomic methods for investigating rheumatic disease cellular function. The core provides consultation on experimental design, service models for sample processing, and state-of-the-art genomics workflows all within centralized data management systems to ensure trustworthy, reproducible results.
Specifically, the GT Core will:
- Develop a state-of-the-art laboratory information management system (LIMS) for tracking biospecimen data for rheumatic disease patients throughout the entire process from sample acquisition to data generation.
- Consolidate the storage and management of the numerous existing rheumatic disease biospecimen collections and facilitate the processing, storage, and management of future biospecimens collected from rheumatic disease patients, from childhood to old age.
- Assemble a panel of experts in genomics and other molecular technologies (including immunologic and proteomic phenotyping) who will provide consultative services related to the appropriate application of genomics and molecular phenotyping of biospecimens for Center rheumatic disease projects.
- Serve as a liaison between investigators and other UCSF laboratory personnel to ensure that high quality genomics and molecular phenotyping data are generated and distributed to the IB Core for integration with clinical data and statistical analysis.